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Recombinant Human SUMO3/SMT3A Protein (aa 1-103, His Tag)
SKU: PKSH033070-50
Recombinant Human SUMO3/SMT3A Protein (aa 1-103, His Tag)
| SKU # | PKSH033070 |
| Expression Host | E.coli |
Description
| Synonyms | SMT3 Homolog 1, SMT3B, SMT3H1, SUMO-2, SUMO-3, SUMO3, Small Ubiquitin-Related Modifier 3, Smt3B, Ubiquitin-Like Protein SMT3B |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Phe103 |
| Accession | P55854 |
| Calculated Molecular Weight | 13.8 kDa |
| Observed Molecular Weight | 19 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
SUMO3 belongs to the SUMO protein family and operates like ubiquitin. Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polyer. Nevertheless unlike ubiquitin that targets proteins for degration; SUMO3 takes part in several cellular processess; such as nuclear transport; transcription regulation; apoptosis and protein stability. SUMO3 participates in amyloid beta generation and has a key role in the oneset or progression of Alzheimer's disease.