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Recombinant Human Syndecan-2/SDC2 Protein (His Tag)(Active)
SKU: PKSH033091-50
Recombinant Human Syndecan-2/SDC2 Protein (His Tag)(Active)
| SKU # | PKSH033091 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CD362, Fibroglycan, HSPG, HSPG1, Heparan Sulfate Proteoglycan Core Protein, SDC2, SYND2, Syndecan-2 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Glu19-Glu144 |
| Accession | AAH49836.1 |
| Calculated Molecular Weight | 15.0 kDa |
| Observed Molecular Weight | 25-40 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-Citrate, 150mM NaCl, pH 7.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Syndecan-2 is a member of the Syndecans family comprised of type I transmembrane heparan sulfate proteoglycans (HSPG) that are involved in the regulation of many cellular processes. Four sub-types of mammalian Syndecans have been reported and among them. Syndecan-2 plays a role in the cancer development. It can affect the basal and chemotherapy-induced apoptosis in osteosarcoma. It can also suppress MMP2 activation, suppressing metastasis.