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Recombinant Human TMPO Protein (His Tag)
SKU: PKSH033116-50
Recombinant Human TMPO Protein (His Tag)
| SKU # | PKSH033116 |
| Expression Host | E.coli |
Description
| Synonyms | LAP2, Lamina-Associated Polypeptide 2 Isoforms Beta/Gamma, Splenin, TMPO, TP, TP Beta/Gamma, TP5, TPRP Isoforms Beta/Gamma, Thymopentin, Thymopoietin, Thymopoietin Isoforms Beta/Gamma, Thymopoietin-Related Peptide Isoforms Beta/Gamma |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met1-Glu187 |
| Accession | P42167 |
| Calculated Molecular Weight | 21.6 kDa |
| Observed Molecular Weight | 27 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domain. The C-terminal domain forms a four-stranded coiled coil. Thymopentin may be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. It is associated with T-cell development and function. Meantime, Thymopentin plays an important role, together with LMNA, in the nuclear anchorage of RB1. Thymopoietin is participated in the induction of CD90 in the thymus.