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Recombinant Human UBE2B/HR6B Protein– MSE Supplies LLC

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Recombinant Human UBE2B/HR6B Protein

SKU: PKSH033179-50

  • $ 47295



Recombinant Human UBE2B/HR6B Protein

 

SKU # PKSH033179
Expression Host E.coli

 

 

Description

Synonyms HR6B, RAD6 Homolog B, RAD6B, UBE2B, Ubiquitin Carrier Protein B, Ubiquitin-Conjugating Enzyme E2 B, Ubiquitin-Conjugating Enzyme E2-17 kDa, Ubiquitin-Protein Ligase B, hHR6B
Species Human
Expression Host E.coli
Sequence Met 1-Ser152
Accession P63146
Calculated Molecular Weight 17.5 kDa
Observed Molecular Weight 18 kDa
Tag None
Bio-activity Not validated for activity
  

 

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 10mM HEPES, pH 7.5.
Reconstitution Not Applicable



Background

Ubiquitin-Conjugating Enzyme E2 B (UBE2B) belongs to the ubiquitin-conjugating enzyme family. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins; and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth.Additionally; UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.