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Recombinant Human UBE2D3 Protein
SKU: PKSH033183-50
Recombinant Human UBE2D3 Protein
| SKU # | PKSH033183 |
| Expression Host | E.coli |
Description
| Synonyms | UBE2D3 and UBCH5C., Ubiquitin carrier protein D3, Ubiquitin-conjugating enzyme E2 D3, Ubiquitin-conjugating enzyme E2(17)KB 3, Ubiquitin-conjugating enzyme E2-17 kDa 3, Ubiquitin-protein ligase D3 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Met 147 |
| Accession | AAH66917 |
| Calculated Molecular Weight | 16.6 kDa |
| Observed Molecular Weight | 15 kDa |
| Tag | None |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 150mM NaCl, 50% Glycerol, 0.05% Tween 80, 1mM TCEP, pH7.1. |
| Reconstitution | Not Applicable |
Background
UBE2D3 is an enzyme that belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.