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Recombinant Human UBE2T Protein (His Tag)
SKU: PKSH030839-50
Recombinant Human UBE2T Protein (His Tag)
| SKU # | PKSH030839 |
| Expression Host | E.coli |
Description
| Synonyms | Cell Proliferation-Inducing Gene 50 Protein, UBE2T, Ubiquitin Carrier Protein T, Ubiquitin-Conjugating Enzyme E2 T, Ubiquitin-Protein Ligase T |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Val197 |
| Accession | Q9NPD8 |
| Calculated Molecular Weight | 23.9 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, 30 % glycerol, 0.1 % Tween 20, 0.4 mM Chaps, pH 7.5 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers; representing an attractive target for the development of inhibitors. Notably; UBE2T locates at 1q32.1; and the gain of 1q is frequently observed in a variety of cancers. For instance; UBE2T serves an important role in the growth of bladder cancer cells; and may be considered as a potential biomarker and therapeutic target for bladder cancer.