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Recombinant Human ZNHIT1 Protein (His Tag)
SKU: PKSH033235-50
Recombinant Human ZNHIT1 Protein (His Tag)
| SKU # | PKSH033235 |
| Expression Host | E.coli |
Description
| Synonyms | CGBP1, ZNFN4A1, ZNHIT1, cyclin-G1-binding protein 1, inc finger HIT domain-containing protein 1, p18 hamlet, zinc finger protein subfamily 4A member 1 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Val154 |
| Accession | O43257 |
| Calculated Molecular Weight | 19.7 kDa |
| Observed Molecular Weight | 21 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4. |
| Reconstitution | Not Applicable |
Background
ZNHIT1 belongs to the ZNHIT1 family and contains one HIT-type zinc finger. It can be phosphorylated on Thr by MAPK11 or MAPK14. ZNHIT1 is a component of the chromatin-remodeling SRCAP complex, which is composed of at least SRCAP, DMAP, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. ZNHIT1 may play a role in p53-mediated apoptosis induction.