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Recombinant Rat CD146/MCAM Protein (His tag)
SKU: PDER100083-100
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Recombinant Rat CD146/MCAM Protein (His tag)
| SKU # | PDER100083 |
| Expression Host | E. coli |
Description
| Synonyms | CD146, Cell surface glycoprotein MUC18, Gicerin, MUC18, Mcam, Melanoma cell adhesion molecule, Melanoma-associated antigen MUC18 |
| Species | Rat |
| Expression Host | E.coli |
| Sequence | His 151-Val 350 |
| Accession | Q9EPF2 |
| Calculated Molecular Weight | 21.9 kDa |
| Observed Molecular Weight | 30 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Melanomia Cell Adhesion Molecule (MCAM), also known as CD146 and MUC18, is a putative Ig-superfamily adhesion molecule that is expressed on endothelial cells and a variety of tumor cells. MCAM is associated with tumor progression and metastasis and may be involved in embryonic neural development. An alternately spliced isoform of rat MCAM has a 40 residue deletion in the cytoplasmic domain.