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Recombinant Rat Clusterin/ApoJ Protein (His tag)
SKU: PDER100064-100
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Recombinant Rat Clusterin/ApoJ Protein (His tag)
| SKU # | PDER100064 |
| Expression Host | E. coli |
Description
| Synonyms | AAG4, AP, APOJ, Aging-Associated Gene 4 Protein, Apo-J, Apolipoprotein J, CLI, CLU, Clusterin, Complement Cytolysis Inhibitor, Complement-Associated Protein SP-40, KUB1, Ku70-Binding Protein 1, NA1/NA2, TRPM-2, Testosterone-Repressed Prostate Message 2 |
| Species | Rat |
| Expression Host | E.coli |
| Sequence | Glu 22-Arg 226 |
| Accession | P05371 |
| Calculated Molecular Weight | 22.4 kDa |
| Observed Molecular Weight | 28 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis; heart; ovary; adrenal gland; brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death; tumor progression; and neurodegenerative disorders. In addition;Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer; organ regeneration; infection; Alzheimer disease; retinitis pigmentosa; myocardial infarction; renal tubular damage; autoimmunity and others.