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Recombinant Rat ST14/Matriptase Protein (His tag)
SKU: PDER100081-100
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Recombinant Rat ST14/Matriptase Protein (His tag)
| SKU # | PDER100081 |
| Expression Host | E. coli |
Description
| Synonyms | Epithin, HAI, MTSP1, Membrane type serine protease 1, PRSS14, Prostamin, SNC19, ST14, Serine protease 14, TADG15, TMPRSS14 |
| Species | Rat |
| Expression Host | E.coli |
| Sequence | Lys 591-Val 855 |
| Accession | Q9JJI7 |
| Calculated Molecular Weight | 29.0 kDa |
| Observed Molecular Weight | 34 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH). ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.