Total Price: $601.95
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RRM1 Monoclonal Antibody Stored at -20°C
SKU: ELAB6973-R-0.1
RRM1 Monoclonal Antibody Stored at -20°C
Product Details
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC-P |
| Synonyms | RRM1 |
| Cellular Localization | Cytoplasm |
| Tissue Specificity | Breast cancer |
| Storage | The concentrated should be stored at -20°C protecting from light,Valid for 12 months. |
| Shipping | Ice bag |
Background
Nucleoside diphosphate reductase large subunit (RRM1) is one of two distinct subunits that comprise nucleoside diphosphate reductase. This enzyme is essential for the production of deoxyribonucleotides prior to S-phase DNA synthesis in dividing cells. RRM1 may reflect carcinogenesis and tumor progression. RRM1 expression is highly correlated with ERCC and PTEN expression in non-small cell lung cancer. Rrm1-positive tumors predicted slow progression.