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Recombinant Human SP-10/ACRV1 Protein (His Tag)
SKU: PKSH032033-50
Recombinant Human SP-10/ACRV1 Protein (His Tag)
| SKU # | PKSH032033 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | ACRV1, Acrosomal Protein SP-10, Acrosomal Vesicle Protein 1, D11S4365, SP-10, SPACA2 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gln22-Ile265 |
| Accession | P26436 |
| Calculated Molecular Weight | 26.9 kDa |
| Observed Molecular Weight | 35 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Acrosomal Protein SP-10 is a testis-specific differentiation antigen that is associated with acrosomal membranes and matrix of mature sperm. It has been detected in several species including humans. Acrosomal Protein SP-10 may be involved in sperm-zona binding or penetration as a potential contraceptive vaccine immunogen for humans. ACRV1 is also a intra-acrosomal protein that is considered to be a vaccine candidate for immunocontraception.