Total Price: $121.95
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ABCE1 Polyclonal Antibody Store at -20°C
SKU: E-AB-10695-200
ABCE1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10695 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ABCE1 |
| Abbre | ABCE1 |
| Synonyms | 2' 5' oligoadenylate binding protein, 2''-5''-oligoadenylate-binding protein, 2'5' oligoadenylate binding protein, ABC 38, ABC38, ABCE 1, ABCE1, ATP binding cassette sub family E (OABP) member 1, ATP binding cassette sub family E member 1, ATP-binding casset |
| Swissprot | |
| Calculated MW | 67 kDa |
| Cellular Localization | Cytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane. |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.