Total Price: $121.95
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ACMSD Polyclonal Antibody Store at -20°C
SKU: E-AB-10712-200
ACMSD Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10712 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ACMSD |
| Abbre | ACMSD |
| Synonyms | 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, ACMSD, Aminocarboxymuconate semialdehyde decarboxylase, Picolinate carboxylase, acmsd |
| Swissprot | |
| Calculated MW | 38 kDa |
| Cellular Localization | Cytosol, Extracellular region or secreted, extracellular exosome. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.