Total Price: $121.95
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CNN3 Polyclonal Antibody Store at -20°C
SKU: E-AB-10711-200
CNN3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10711 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CNN3 |
| Abbre | CNN3 |
| Synonyms | Acidic calponin 3, CNN 3, CNN3, Calponin, Calponin 3, Calponin 3 acidic, Calponin acidic, Calponin acidic isoform, Calponin-3, Calponin3, Cnn3, OTTHUMP00000012470, OTTHUMP00000012471, acidic isoform, dJ639P13.2.2 |
| Swissprot | |
| Calculated MW | 36 kDa |
| Cellular Localization | Cytoskeleton, actin cytoskeleton, Cytosol, Other locations: cell-cell adherens junction, dendritic spine, focal adhesion, neuronal cell body, postsynaptic density. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.