MSE PRO 7-Benzyl-1,7-diazaspiro[4.5]decane, ≥95.0% Purity

MSE PRO™ 7-Benzyl-1,7-diazaspiro[4.5]decane, ≥95.0% Purity

MSE PRO™ 7-Benzyl-1,7-diazaspiro[4.5]decane features a distinctive spirocyclic pyrrolidine scaffold, which imparts structural rigidity and conformational constraints, making it an attractive building block for modulating biological targets. Spirocyclic pyrrolidines have garnered significant interest in medicinal chemistry due to their potential as therapeutic agents for various diseases, including obesity, diabetes, and neurological disorders. This compound presents an opportunity to explore its biological activity and develop novel derivatives.

MSE Supplies offers various N-heterocyclic drug small molecules and other chemical reagents. Please contact us for bulk orders.

Technical Specifications:

References:

[1] Smith, A. C., Cabral, S., Kung, D. W., Rose, C. R., Southers, J. A., García-Irizarry, C. N., ... & Griffith, D. A. (2016). The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2, 7-Diazaspiro [3.5] nonane) and Spirocyclic Piperidine-Pyrrolidine (2, 8-Diazaspiro [4.5] decane) Ring Systems. The Journal of Organic Chemistry, 81(9), 3509-3519.

[2] Niu, A., Lin, L., Zhang, D., Jiang, K., Weng, D., Zhou, W., & Wang, J. (2022). Discovery of novel 2, 8-diazaspiro [4.5] decan-1-one derivatives as potent RIPK1 kinase inhibitors. Bioorganic & Medicinal Chemistry, 59, 116686.