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MSE PRO tBuBrettphos, 98% Purity– MSE Supplies LLC

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MSE PRO Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (tBuBrettphos), 98% Purity - MSE Supplies LLC

MSE PRO Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (tBuBrettphos), 98% Purity

SKU: CM1317

  • $ 29995
  • Save $ 4805

MSE PRO™ Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (tBuBrettphos), 98% Purity

MSE PRO™ Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine (tBuBrettphos) is a highly efficient dialkylbiaryl phosphine ligand developed by the Buchwald group. It is renowned for its significant enhancement of cross-coupling reactions and reactivity in comparison to alternative catalytic systems. Notable examples of its effectiveness include its application in Pd-catalyzed conversion reactions of aryl and vinyl triflates, O-arylation of ethyl acetohydroximates, and conversion of aryl chlorides, triflates, and nonaflates to nitroaromatics.

MSE Supplies offers various catalysts and ligands of coupling reaction. Please contact us for customization or bulk orders.

Technical Specifications:

CAS No. 1160861-53-9
EINECS No. 811-756-3
Chemical name Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine
Synonym(s)
  • tBuBrettPhos

  • Di(tert-butyl)(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine
Molecular formula C31H49O2P
Pack size

1 g (CM1317)

5 g (CM1318)
Molecular weight 484.7 g/mol
Purity 98 %
Melting point 166-170 °C
Appearance White solid
Storage  Keep in Inert atmosphere, store at 2-8°C.


References:

[1] Gioria, E., Del Pozo, J., Martínez‐Ilarduya, J. M., & Espinet, P. (2016). Promoting difficult carbon–carbon couplings: which ligand does best?. Angewandte Chemie, 128(42), 13470-13474.

[2] Seo, T., Kubota, K., & Ito, H. (2020). Selective mechanochemical monoarylation of unbiased dibromoarenes by in situ crystallization. Journal of the American Chemical Society, 142(22), 9884-9889.