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MSE PRO LC-MS/MS Liquid Chromatograph – Triple Quadrupole Mass Spectrometer
SKU: MA2630
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MSE PRO™ LC-MS/MS Liquid Chromatograph – Triple Quadrupole Mass Spectrometer
Overview
The MSE PRO LC-MS/MS Liquid Chromatograph – Triple Quadrupole Mass Spectrometer combines the high separation efficiency of liquid chromatography with the powerful identification capabilities of mass spectrometry. It offers excellent sensitivity, selectivity, stability, and strong anti-interference performance, making it ideal for the qualitative and quantitative analysis of trace pesticides and veterinary drugs in complex matrices with high sensitivity.
Working Environment
- Work environment temperature: 18-25 ℃
- Humidity in work environment: (20 ~ 60)% RH
- Power supply: five sets of single-phase (220 ± 20) V AC, 10A, 50 Hz power supply
Workstation Software
The software system is compatible with Windows XP and later operating systems. It provides full control over the liquid chromatograph and mass spectrometer, featuring built-in data processing and report editing capabilities. Additionally, it supports automatic instrument configuration, condition optimization, quantitative analysis, mass spectrometry data interpretation, and spectral database creation and retrieval.
Key functionalities include automatic calibration and real-time instrument condition monitoring. The LC-MS operation software can be installed on a personal computer, enabling offline processing of sample analysis data and seamless report generation.
System Configuration & Specification
| Configuration and Performance Indicators of Liquid Chromatograph | |
| 1. Ultra-high pressure gradient pump | |
| Two solutions in A and B, or C and D, can be selected as the flowing phase of the system by switching the solvent selection valve. | |
| A vacuum degasser is equipped, with each pump degassing separately (A/B). | |
| Flow range | 1-4,000 µL/min |
| Maximum pressure | ≥ 18,850psi |
| Accuracy of flow rate | ≤1% |
| Precision of flow rate | ≤ 0.075% RSD |
| 2. Automatic sample injector | |
| Three injection modes | full loop injection, partial loop injection and microliter pickup. |
| Injection repeatability | Full loop injection <0.3% RSD; partial loop injection <0.3% RSD; microliter pickup <1.0% RSD |
| Cross contamination | <0.05% |
| Maximum sample capacity | 384 bits, and 96 bits for standard liquid injection. |
| 3. Column oven | |
| Temperature control range | Room temperature +5 ℃ – 90 ℃ |
| Temperature control mode | preheating of flowing phase + forced air circulation |
| Maximum column capacity | Six 250mm long chromatographic columns can be installed at the same time. |
| Requirements for configuration and performance indicators of mass spectrometry system | |
| 1. Ion source (spray ion source for standard configuration) | |
| Orthogonal vertical spray design is adopted, so that the system has strong anti-pollution capacity and low background noise. | |
| Ion source gas supply | 1 loop of nitrogen for atomizing and 2 loops of nitrogen for desolvation. Specifically, the flow rate of nitrogen for atomizing is 0-2 L/min, and that for desolvation is 0-15 L/min. The maximum spray voltage is 6kV. The flow rate, voltage and temperature can be set up and run under the software interface, to ensure the maximum ionization efficiency and resistance to matrix interference. |
| A special exhaust device is set in the ion source to prevent the backflow of gas in the closed ion source cavity, further to reduce the memory effect and pollution of the ion source, decrease the load of the mechanical pump, prolong the service time of the mechanical pump oil, maintain the test environment and ensure the health of the staff. | |
| 2. Vacuum interface and ion transmission system | |
| High temperature blowback gas design | Nitrogen is used as the blowback gas, with a flow rate of 0-5L/min to further remove the solvent and reduce the introduction of neutral molecules. |
| Heating design of vacuum interface | It can be heated to 110 ℃ at most to improve the anti-pollution capacity. |
| Vacuum interface maintenance | simple cleaning and maintenance, without vacuum unloading. The whole process of daily maintenance and installation can be easily completed in a few minutes. |
| Ion transmission system | 4-stage differential vacuum design is adopted, and multiple quadrupole transmission is used for accurate focusing of ions. |
| 3. Mass analysis system | |
| Mass analyzer | Triple quadrupole mass analyzer. |
| Quadrupole | Made of high-precision pure Mo material, capable of ensuring the best mass axis stability. |
| Collision cell | Axial acceleration design is adopted, capable of effectively eliminating the interference of ion pair and ensuring the high-throughput analysis capability. Nitrogen (with purity ≥ 99.999%) is used as the collision gas and supplied in cylinder. |
| Resolution | 0.4-2 amu (adjustable) |
| Mass stability | better than 0.1amu/24 hours. |
| Scanning speed | ≥ 20,000 amu/s |
| Number of MRM channels | 100 channels/s |
| Mass range m/z | 5 – 1,000amu. |
| Dynamic range | 6 orders of magnitude. |
| Sensitivity | ESI+, MRM mode: 1pg reserpine, injected on the column, with S/N≥100000:1ESI-, MRM mode: 1pg chloramphenicol, injected on the column, with S/N ≥ 100,000:1; |
| Scanning functions | Full scan, selected ion monitoring (SIM), product ion scan, precursor ion scan, neutral loss scan, multiple reaction monitoring (MRM), positive/negative ion switching scan, etc. |
| 4. Detector | |
| Multiplier technology, without any positive and negative ion discrimination effect, which has long service life, capable of ensuring the long-term data stability. | |
| Pulse-counting detector, to ensure the data reproducibility of low limit of detection. | |
| Positive/negative polarity switching time | ≤ 50ms |
| Vacuum system | composed of a mechanical pump and a turbo molecular pump, with a differential pumping system formed between the ion transmission area and mass analysis area, functioning for automatic power-off protection. |
Accessory system
- Computer system: Brand computer with mainstream configuration, 4GB memory, 1TB hard disk.
- AC stabilized power supply: 15KVA, input voltage of 140v-300v, output voltage of 220 V ± 1%.
- Laser printer: 6018L, black and white laser printer.
- Nitrogen generator: The maximum flow is 24L/min and the maximum pressure is 116psi.
- Mechanical pump: Pumping speed: 65m3/h, 220V power supply, 800W.
Optional Parts
The optional components are available for order upon request.
| SKU# | Parts | Price | |
| MA2631 | 6-column oven without switching valve and cooling function | $6,669.95 | |
| MA2632 | 6-column oven with switching valve and cooling function | $15,839.95 | |
| MA2633 | Single column oven without cooling function | $4999.95 | |
| MA2634 | Single column oven with cooling function | $7,499.95 | |