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Recombinant Bovine TGFBR1 protein (His tag)
SKU: PDEB100004-100
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Recombinant Bovine TGFBR1 protein (His tag)
| SKU # | PDEB100004 |
| Expression Host | E. coli |
Description
| Synonyms | TGF beta Receptor I;AAT5;Activin A receptor type II like kinase 53kDa;Activin receptor like kinase 5;ACVRLK 4;ALK 5;LDS1A;MSSE;Serine/threonine-protein kinase receptor R4;SKR4;TbetaR-I;TGFR 1 |
| Species | Bovine |
| Expression_host | E.coli |
| Sequence | Ile 143-Leu 330 |
| Accession | O46680 |
| Mol_Mass | 20.6 kDa |
| AP_Mol_Mass | 20 kDa |
| Tag | N-His |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.