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Recombinant Human 14-3-3 eta/YWHAH Protein (GST Tag)
SKU: PKSH031391-100
Recombinant Human 14-3-3 eta/YWHAH Protein (GST Tag)
| SKU # | PKSH031391 |
| Expression Host | E.coli |
Description
| Synonyms | YWHA1 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Gly 2-Asn 246 |
| Accession | Q04917 |
| Calculated Molecular Weight | 55.0 kDa |
| Observed Molecular Weight | 55 kDa |
| Tag | N-GST |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile 20mM Tris, 0.15M NaCl, 20mM GST, pH 8.0 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
YWHAH, the gene encoding the 14-3-3eta isoform, is highly expressed in retinal ganglion cells (RGC). YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). It is located on chromosome 22q12.3, a region which has been implicated by linkage studies in both BP and schizophrenia.