Total Price: $0.00
Contact Information
Recombinant Human ACP1/LMW-PTP Protein (His Tag)
SKU: PKSH033598-50
Recombinant Human ACP1/LMW-PTP Protein (His Tag)
| SKU # | PKSH033598 |
| Expression Host | E.coli |
Description
| Synonyms | ACP1, Adipocyte Acid Phosphatase, HAAP, LMW-PTP, LMW-PTPase, Low Molecular Weight Cytosolic Acid Phosphatase, Low Molecular Weight Phosphotyrosine Protein Phosphatase, Red Cell Acid Phosphatase 1 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Ala2-His158 |
| Accession | P24666-2 |
| Calculated Molecular Weight | 19.0 kDa |
| Observed Molecular Weight | 18 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphatase (PTPase) by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. LMW-PTP can be detected in all human tissues, including adipocytes. LMW-PTP is a cytosolic enzyme that regulate cell proliferation and growth of leiomyomas during dephosphorylation of the PDGF receptor. In addition, LMW-PTP plays an important role in the regulation of physiological functions, such as stress resistance and synthesis of the polysaccharide capsule.