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Recombinant Human AGR3 Protein (His Tag)
SKU: PKSH032080-50
Recombinant Human AGR3 Protein (His Tag)
| SKU # | PKSH032080 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | AG-3, AG3, AGR3, Anterior Gradient Protein 3 Homolog, BCMP11, Breast Cancer Membrane Protein 11, hAG-3 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ile22-Leu166 |
| Accession | Q8TD06 |
| Calculated Molecular Weight | 18.0 kDa |
| Observed Molecular Weight | 16 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Glycine-HCl, 10% Trehalose, 0.05% Tween 80, pH3.5. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan (hAG-3 protein). AG-3 could serve as a prognostic marker for survival in patients with low grade and high grade serous ovarian carcinomas.