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Recombinant Human Arginase-2/ARG2 Protein (His Tag)
SKU: PKSH032673-50
Recombinant Human Arginase-2/ARG2 Protein (His Tag)
| SKU # | PKSH032673 |
| Expression Host | E.coli |
Description
| Synonyms | ARG2 , Arginase-2, Kidney-type arginase, Non-hepatic arginase, Type II arginase, mitochondrial |
| Species | Human |
| Expression Host | E.coli |
| Sequence | His24-Gly330 |
| Accession | P78540 |
| Calculated Molecular Weight | 34.2 kDa |
| Observed Molecular Weight | 33 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, pH 7.5. |
| Reconstitution | Not Applicable |
Background
Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not founded in the liver, heart and pancreas. ARG2 has been implicated in the regulation of the arginine/ornithine concentrations in the cell. ARG2 may take part in the regulation of extra-urea cycle arginine metabolism and in down-regulation of nitric oxide synthesis. The extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase.