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Recombinant Human Cathepsin Z Protein (His Tag)– MSE Supplies LLC

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Recombinant Human Cathepsin Z Protein (His Tag)

SKU: PKSH033443-50

  • $ 53395
  • Save $ 6000



Recombinant Human Cathepsin Z Protein (His Tag)

 

SKU # PKSH033443
Expression Host HEK293 Cells

 

 

Description

Synonyms CTSZ, Cathepsin P, Cathepsin X, Cathepsin Z
Species Human
Expression Host HEK293 Cells
Sequence Gly24-Val303
Accession Q9UBR2
Calculated Molecular Weight 32.5 kDa
Observed Molecular Weight 37-40 kDa
Tag C-His
Bio-activity Not validated for activity
  

 

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of 4mM HCl.
Reconstitution Not Applicable



Background

Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence; a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B; it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system; predominantly monocytes; macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family; Cathepsin Z may be involved in tumorigenesis.