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Recombinant Human CD200R1 Protein (His & Fc Tag)(Active)– MSE Supplies LLC

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Recombinant Human CD200R1 Protein (His & Fc Tag)(Active)

SKU: PKSH031201-100

  • $ 65895
  • Save $ 7400



Recombinant Human CD200R1 Protein (His & Fc Tag)(Active)

 

SKU # PKSH031201
Expression Host HEK293 Cells

 

 

Description

Synonyms CD200R, HCRTR2, MOX2R, OX2R
Species Human
Expression Host HEK293 Cells
Sequence Met 1-Leu 266
Accession AAI43394.1
Calculated Molecular Weight 54.9 kDa
Observed Molecular Weight 90-100 kDa
Tag C-His-Fc
Bio-activity Immobilized recombinant human CD200 at 1 μg/ml (100ul/well) can bind human CD200R1 / Fc Chimera with a linear range of 0.12-16 ng/ml.
  

 

Properties

Purity > 94 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.


Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cell surface glycoprotein CD200 receptor 1 (CD200R1) is an isoform of CD200 receptors which is expressed on cells of the myeloid lineage. CD200R1 is a receptor for the OX-2 membrane glycoprotein. The receptor-substrate interaction may serve as a myeloid downregulatory signal.