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Recombinant Human CD83/HB15 Protein (Fc Tag)
SKU: PKSH032226-50
Recombinant Human CD83/HB15 Protein (Fc Tag)
| SKU # | PKSH032226 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | B-Cell Activation Protein, CD83, CD83 Antigen, Cell Surface Protein HB15, hCD83 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Thr 20-Ala143 |
| Accession | Q01151 |
| Calculated Molecular Weight | 41.2 kDa |
| Observed Molecular Weight | 50-60 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
CD83 antigen is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. CD83 is expressed by activated lymphocytes; Langerhans cells and interdigitating reticulum cells. It contains one Ig-like V-type (immunoglobulin-like) domain. ; the soluble CD83 has the opposite effect and has an immune inhibitory capacity. Due to its immune inhibitory function; CD83 may play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.