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Recombinant Human CEACAM1/CD66a Protein (His Tag)– MSE Supplies LLC

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Recombinant Human CEACAM1/CD66a Protein (His Tag)

SKU: PKSH033739-50

  • $ 23595
  • Save $ 2700



Recombinant Human CEACAM1/CD66a Protein (His Tag)

 

SKU # PKSH033739
Expression Host HEK293 Cells

 

 

Description

Synonyms BGP, BGP-1, BGP1, Biliary Glycoprotein 1, CD66a, CEACAM1, Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1
Species Human
Expression Host HEK293 Cells
Sequence Gln35-Gly428
Accession P13688
Calculated Molecular Weight 44.3 kDa
Observed Molecular Weight 60-90 kDa
Tag C-His
Bio-activity Not validated for activity
  

 

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.



Background

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.