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Recombinant Human CPVL/VCP-Like Protein (His Tag)
SKU: PKSH032931-50
Recombinant Human CPVL/VCP-Like Protein (His Tag)
| SKU # | PKSH032931 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CPVL, Carboxypeptidase vitellogenic-like, Probable serine carboxypeptidase CPVL, VCP-like protein, Vitellogenic carboxypeptidase-like protein |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Leu23-Gly476 |
| Accession | AAH16838.1 |
| Calculated Molecular Weight | 52.9 kDa |
| Observed Molecular Weight | 54-65 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
| Reconstitution | Not Applicable |
Background
Probable serine carboxypeptidase CPVL, also known as Carboxypeptidase, vitellogenic-like, Vitellogenic carboxypeptidase-like protein, is a member of the peptidase S10 family. It is expressed in macrophages but not in other leukocytes. And specifically, it is abundantly expressed in heart and kidney, also expressed in spleen, leukocytes, and placenta. This enzyme may be involved in the digestion of phagocytosed particles in the lysosome, and also participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation.