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Recombinant Human CXCL10 protein (His tag)
SKU: PDEH100230-100
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Recombinant Human CXCL10 protein (His tag)
| SKU # | PDEH100230 |
| Expression Host | E. coli |
Description
| Synonyms | C-X-C Motif Chemokine 10;10 kDa Interferon Gamma-Induced Protein;Gamma-IP10;IP-10;Small-Inducible Cytokine B10;CXCL10;INP10;SCYB10 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Val 22-Pro 98 |
| Accession | P02778 |
| Mol_Mass | 8.4 kDa |
| AP_Mol_Mass | 12 kDa |
| Tag | C-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types; such as monocytes; endothelial cells and fibroblasts; in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles; such as chemoattraction for activated T-lymphocytes; inhibition of angiogenesis; and antitumor activity.