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Recombinant Human ERP44 Protein (His Tag)
SKU: PKSH032399-50
Recombinant Human ERP44 Protein (His Tag)
| SKU # | PKSH032399 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | ER protein 44, KIAA0573, TXNDC4, Thioredoxin domain-containing protein 4 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Glu30-Asp402 |
| Accession | Q9BS26 |
| Calculated Molecular Weight | 44.2 kDa |
| Observed Molecular Weight | 50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 7.5. |
| Reconstitution | Not Applicable |
Background
Endoplasmic reticulum resident protein 44 (TXNDC4) is is a 406 amino acid protein that contains one thioredoxin domain. TXNDC4 mediates thiol-dependent retention in the early secretory pathway and forms mixed disulfides with substrate proteins through its conserved CRFS motif.It can inhibit the calcium channel activity of ITPR1.It may have a role in the control of oxidative protein folding in the endoplasmic reticulum.