Recombinant Human ERP72/PDIA4 Protein (aa 1-641, His Tag)
SKU: PKSH030654-100
Recombinant Human ERP72/PDIA4 Protein (aa 1-641, His Tag)
SKU # | PKSH030654 |
Expression Host | HEK293 Cells |
Description
Synonyms | ER Protein 70, ER Protein 72, ERP70, ERP72, ERp-72, ERp70, ERp72, Endoplasmic Reticulum Resident Protein 70, Endoplasmic Reticulum Resident Protein 72, PDIA4, Protein Disulfide-Isomerase A4 |
Species | Human |
Expression Host | HEK293 Cells |
Sequence | Met 1-Thr641 |
Accession | P13667 |
Calculated Molecular Weight | 71.6 kDa |
Observed Molecular Weight | 67 kDa |
Tag | C-His |
Bio-activity | Not validated for activity |
Properties
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | Please refer to the printed manual for detailed information. |
Background
ERP72; also known as PDIA4; is an endoplasmic reticulum luminal protein which belongs to the protein disulfide isomerase family. ERP72 is a stress protein and participates in the catalysis of protein-S-S-bond rearrangement. Both of PDIA4 and PDIA3 function as proteases; protein disulfide isomerases; phospholipases or an arrangement of these. ERP72 compose part of a large chaperone multiprotein complex comprising CABP1; DNAJB11; HSP90B1; HSPA5; HYOU; PDIA2; PDIA4; PPIB; SDF2L1; UGT1A1 and very small amounts of ERP29; but not; or at very low levels; CALR nor CANX.