Total Price: $0.00
Contact Information
Recombinant Human FKBP2 Protein (His Tag)
SKU: PKSH032875-50
Recombinant Human FKBP2 Protein (His Tag)
| SKU # | PKSH032875 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | FK506-binding protein 2, Immunophilin FKBP13, Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), Rotamase, also named 13 kDa FK506-binding protein |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ala22-Leu142 |
| Accession | P26885 |
| Calculated Molecular Weight | 14.3 kDa |
| Observed Molecular Weight | 17 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mm NaCl, pH 7.5. |
| Reconstitution | Not Applicable |
Background
Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds.