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Recombinant Human FSH-b protein (His tag)
SKU: PDEH100120-100
Recombinant Human FSH-b protein (His tag)
| SKU # | PDEH100120 |
| Expression Host | E. coli |
Description
| Synonyms | Follitropin Subunit Beta;Follicle-Stimulating Hormone Beta Subunit;FSH-B;FSH-Beta;Follitropin Beta Chain;FSHB |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Met1-Glu129 |
| Accession | P01225 |
| Mol_Mass | 14.1 kDa |
| AP_Mol_Mass | 28 kDa |
| Tag | C-His |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Follitropin Subunit β (FSHB) is a secreted protein that belongs to the glycoprotein hormones subunit β family. The pituitary glycoprotein hormone family includes follicle-stimulating hormone, luteinizing hormone, chorionic gonadotropin, and thyroid-stimulating hormone. FSHB exists in a heterodimer of a common α chain and an unique β chain that confers biological specificity to thyrotropin, lutropin, follitropin, and gonadotropin. FSHB stimulates development of follicle and spermatogenesis in the reproductive organs. Defects in FSHB are a cause of isolated follicle-stimulating hormone deficiency (IFSHD).