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Recombinant Human FUT8 Protein (aa 68-575, His Tag)(Active)– MSE Supplies LLC

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Recombinant Human FUT8 Protein (aa 68-575, His Tag)(Active)

SKU: PKSH031148-50

  • $ 65895
  • Save $ 7400



Recombinant Human FUT8 Protein (aa 68-575, His Tag)(Active)

 

SKU # PKSH031148
Expression Host Baculovirus-Insect Cells

 

Description

Synonyms MGC26465
Species Human
Expression Host Baculovirus-Insect Cells
Sequence Arg 68-Lys 575
Accession Q9BYC5-1
Calculated Molecular Weight 60.0 kDa
Observed Molecular Weight 55 kDa
Tag C-His
Bio-activity Measured by its ability to hydrolyze the donor substrate GDP fucose. The specific activity is > 0.75 pmoles/min/μg.
  

 

Properties

Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 10% glycerol
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.


Background

Alpha (1,6) fucosyltransferase 8, also known as FUT8, is a member of the glycosyltransferase family. Fucosyltransferases are the enzymes transferring fucose from GDP-Fuc to Gal in an alpha1,2-linkage and to GlcNAc in alpha1,3-linkage, alpha1,4-linkage, or alpha1,6-linkage. All fucosyltransferases utilize the same nucleotide sugar, their specificity reside in the recognition of the acceptor and in the type of linkage formed. Fucosyltransferases share some common structural and catalytic features. On the basis of protein sequence similarities, these enzymes can be classified into four distinct families: (1) the alpha-2-fucosyltransferases, (2) the alpha-3-fucosyltransferases, (3) the mammalian alpha-6-fucosyltransferases, and (4) the bacterial alpha-6-fucosyltransferases. The alpha-3-fucosyltransferases constitute a distinct family as they lack the consensus peptide, but some regions display similarities with the alpha-2 and alpha-6-fucosyltranferases.