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Recombinant Human GSK3α Protein
SKU: PDEH100084-100
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Recombinant Human GSK3α Protein
| SKU # | PDEH100084 |
| Expression Host | E. coli |
Description
| Synonyms | Glycogen synthase kinase-3 alpha;GSK-3 alpha;Serine/threonine-protein kinase GSK3A;GSK3A |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Ser97-Pro448 |
| Accession | P49840 |
| Mol_Mass | 39.4 kDa |
| AP_Mol_Mass | 39 kDa |
| Tag | N-His |
Properties
| Purity | > 80 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4.5% trehalose, 5% mannitol, 0.01% Tween 80. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1.