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Recombinant Human HPCAL1 Protein (His Tag)
SKU: PKSH032547-50
Recombinant Human HPCAL1 Protein (His Tag)
| SKU # | PKSH032547 |
| Expression Host | E.coli |
Description
| Synonyms | BDR1, Calcium-Binding Protein BDR-1, HLP2, HPCAL1, Hippocalcin-Like Protein 1, VILIP-3, Visinin-Like Protein 3 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Phe193 |
| Accession | P37235 |
| Calculated Molecular Weight | 24.5 kDa |
| Observed Molecular Weight | 21 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Hippocalcin-Like Protein 1 (HPCAL1) is a neuron-specific calcium-binding member of the recoverin family which found in the retina and brain. HPCAL1 contains four EF-hand domains and it is highly similar to human hippocalcin protein. HPCAL1 is involved in the calcium-dependent regulation of rhodopsin phosphorylation. In addition, it may be of relevance for neuronal signalling in the central nervous system.