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Recombinant Human Inhibin β C Chain/INHBC Protein (aa 237-352, His Tag)(Active)
SKU: PKSH032587-50
Recombinant Human Inhibin β C Chain/INHBC Protein (aa 237-352, His Tag)(Active)
| SKU # | PKSH032587 |
| Expression Host | E.coli |
Description
| Synonyms | Activin Beta-C Chain, INHBC, Inhibin Beta C Chain |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Gly237-Ser352 |
| Accession | P55103 |
| Calculated Molecular Weight | 14.8 kDa |
| Observed Molecular Weight | 16 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 4mM HCl, 1mM DTT. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion; gonadal hormone secretion; germ cell development and maturation; erythroid differentiation; insulin secretion; nerve cell survival; embryonic axial development or bone growth; depending on their subunit composition. Inhibins appear to oppose the functions of activins;Inhibins and activins inhibit and activate; respectively; the secretion of follitropin by the pituitary gland.