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Recombinant Human Kallikrein 6/KLK6 Protein (His tag)
SKU: PDEH100302-100
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Recombinant Human Kallikrein 6/KLK6 Protein (His tag)
| SKU # | PDEH100302 |
| Expression Host | E. coli |
Description
| Synonyms | Kallikrein-6;Neurosin;Protease M;SP59;Serine Protease 18;Serine Protease 9;KLK6;PRSS18;PRSS9 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Glu 81-Lys 244 |
| Accession | Q92876 |
| Mol_Mass | 25.8 kDa |
| AP_Mol_Mass | 20 kDa |
| Tag | N-His |
| Bio_Activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin level | Please contact us for more information. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Tissue kallikreins are a family of extracellular serine proteases consisting of 15 members . The genes of this family aligned in tandem on chromosome 19q13.4 represent the largest contiguous group of proteases within the human genome. Tissue kallikreins have attracted great interest as potential biomarkers for various cancers, including prostate, ovarian, breast, testicular, and lung (2, 3). Human Kallikrein 6 (hKLK6) is a member of tissue kallikrein family observed in breast and brain tissues, colon carcinoma cells, and oligodedrocytes.