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Recombinant Human KIR2DL3 Protein (His tag)– MSE Supplies LLC

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Recombinant Human KIR2DL3 protein (His tag)

Recombinant Human KIR2DL3 Protein (His tag)

SKU: PDMH100139-100

  • $ 44995
  • Save $ 5000



Recombinant Human KIR2DL3 Protein (His tag)

 

SKU # PDMH100139
Expression Host HEK293 Cells

 

Description    

Synonyms KIR2DL3, Natural killer cell inhibitory receptor
Species Human
Expression Host HEK293 Cells
Sequence Met1-His245
Accession Q32WE4
Calculated Molecular Weight 26.8 kDa
Observed Molecular Weight 42 kDa
Tag C-His
Bio-activity Not validated for activity
  

 

Properties

Purity > 95% as determined by reducing SDS-PAGE.
Endotoxin Please contact us for more information.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.


Background

Killer cell immunoglobulin-like receptor 2DL3, also known as CD158 antigen-like family member B2, KIR-23GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2, and KIR2DL3, is a single-pass type I membrane protein which belongs to the immunoglobulin superfamily. KIR2DL3 contains 2 Ig-like C2-type (immunoglobulin-like) domains. KIR2DL3 interacts with ARRB2. KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3, and HLA-Cw7). KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.