Total Price: $0.00
Contact Information
Recombinant Human KLF6 Protein
SKU: PKSH032677-50
Recombinant Human KLF6 Protein
| SKU # | PKSH032677 |
| Expression Host | E.coli |
Description
| Synonyms | B-Cell-Derived Protein 1, BCD1, COPEB, CPBP, Core Promoter Element-Binding Protein, GC-Rich Sites-Binding Factor GBF, KLF6, Krueppel-Like Factor 6, Proto-Oncogene BCD1, ST12, Suppressor of Tumorigenicity 12 Protein, Transcription Factor Zf9 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Ser109 |
| Accession | Q99612-3 |
| Calculated Molecular Weight | 12.6 kDa |
| Observed Molecular Weight | 13-19 kDa |
| Tag | None |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer.