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Recombinant Human KLK10 Protein (His Tag)
SKU: PDEH100018-100
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Recombinant Human KLK10 Protein (His Tag)
| SKU # | PDEH100018 |
| Expression Host | E. coli |
Description
| Synonyms | Breast normal epithelial cell associated serine protease;Kallikrein related peptidase 10;Kallikrein10;KLK 10;KLK10;NES 1;NES1;Normal epithelial cell-specific 1;Protease serine like 1;Protease serine-like 1;PRSS L1;PRSSL 1;PRSSL1 |
| Species | Human |
| Expression_host | E.coli |
| Sequence | Ala31-Asn276 |
| Accession | O43240-1 |
| Mol_Mass | 27.0 kDa |
| AP_Mol_Mass | 29.28 kDa |
| Tag | N-His |
Properties
| Purity | > 80 % as determined by reducing SDS-PAGE. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.