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Recombinant Human Lymphotactin/XCL1 Protein (Fc & His Tag)
SKU: PKSH032717-50
Recombinant Human Lymphotactin/XCL1 Protein (Fc & His Tag)
| SKU # | PKSH032717 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | ATAC, C motif chemokine 1, Cytokine SCM-1, LTN, Lymphotactin, Lymphotaxin, SCM-1-alpha, SCYC1 and XCL1, Small-inducible cytokine C1, XC chemokine ligand 1 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Val22-Gly114 |
| Accession | P47992 |
| Calculated Molecular Weight | 38.2 kDa |
| Observed Molecular Weight | 54 kDa |
| Tag | C-Fc-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. XCL1 plays a role in inflammatory and immunological responses, inducing leukocyte migration and activation. XCL1 induces chemotactic function by binding to a chemokine receptor called XCR1. XCL1 is closely related to another chemokine called XCL2.