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Recombinant Human LYPLA2 Protein (His Tag)
SKU: PKSH033332-50
Recombinant Human LYPLA2 Protein (His Tag)
| SKU # | PKSH033332 |
| Expression Host | E.coli |
Description
| Synonyms | APT-2, APT2, Acyl-Protein Thioesterase 2, LPL-II, LYPLA2, LysoPLA II, Lysophospholipase II |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Val231 |
| Accession | O95372 |
| Calculated Molecular Weight | 25.8 kDa |
| Observed Molecular Weight | 28 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 100mM Nacl, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Acyl-Protein Thioesterase 2 is a cytoplasmic protein that belongs to the AB Hydrolase 2 family. LYPLA2 is a lysophospholipase and hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. LYPLA2 has hydrolase activity that converts Palmitoyl-protein to palmitate and protein. LYPLA2 regulates the multifunctional lysophospholipids by acting on biological membranes. LYPLA2 participates in Glycerophospholipid metabolism pathway; fatty acid metabolic process and lipid metabolic process.