Total Price: $0.00
Contact Information
Recombinant Human MOG Protein (E.coli, His Tag)
SKU: PKSH032768-50
Recombinant Human MOG Protein (E.coli, His Tag)
| SKU # | PKSH032768 |
| Expression Host | E.coli |
Description
| Synonyms | BTN6, BTNL11, MOG, MOGIG2, Myelin-Oligodendrocyte Glycoprotein, NRCLP7 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Gly30-Gly154 |
| Accession | Q16653 |
| Calculated Molecular Weight | 15.2 kDa |
| Observed Molecular Weight | 16-18 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals; namely experimental autoimmune encephalomyelitis (EAE); in rodents and monkeys.