Total Price: $0.00
Contact Information
Recombinant Human NPDC-1/NPDC1 Protein (His Tag)
SKU: PKSH032822-50
Recombinant Human NPDC-1/NPDC1 Protein (His Tag)
| SKU # | PKSH032822 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CAB, CAB-1, CAB1, NPDC-1, NPDC1, Neural Proliferation Differentiation and Control Protein 1, RP11-229P13.1 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Gly35-Asp181 |
| Accession | Q9NQX5 |
| Calculated Molecular Weight | 16.5 kDa |
| Observed Molecular Weight | 28-35 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Neural proliferation differentiation and control protein 1(NPDC1) is a protein that in humans is encoded by the NPDC1 gene. It is a single-pass membrane protein and belongs to the NPDC1/cab-1 family. The protein strongly expressed in adult brain and especially in hippocampus; frontal lobe and temporal lobe. The protein suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation and it might be involved in transcriptional regulation.