Recombinant Human OFQ/N protein (His tag)
SKU: PDEH100149-100
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Recombinant Human OFQ/N protein (His tag)
SKU # | PDEH100149 |
Expression Host | E. coli |
Description
Synonyms | PNOC;N/OFQ;NOP;OFQ;PPNOC;ppN/OFQ;Prepronociceptin |
Species | Human |
Expression_host | E.coli |
Sequence | Ser 20-Val 176 |
Accession | Q13519 |
Mol_Mass | 17.2 kDa |
AP_Mol_Mass | 23 kDa |
Tag | N-His |
Bio_Activity | Not validated for activity |
Properties
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin level | Please contact us for more information. |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis |
Background
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally regulate body temperature, learning and memory, and hunger. Another product of the encoded preproprotein, nocistatin, may inhibit the effects of nociceptin.