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Recombinant Human PFK1/PFKM Protein (His Tag)
SKU: PKSH032890-50
Recombinant Human PFK1/PFKM Protein (His Tag)
| SKU # | PKSH032890 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | 6-phosphofructokinase, ATP-PFK, GSD7, PFK-1, PFK1, PFKA, PFKM, PFKX, PPP1R122, Phosphofructo-1-kinase isozyme A, Phosphofructokinase 1, Phosphohexokinase, muscle type |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Thr 2-Val 780 |
| Accession | P08237 |
| Calculated Molecular Weight | 86.1 kDa |
| Observed Molecular Weight | 93 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5mM EDTA, 5% Trehalose, pH 6.9. |
| Reconstitution | Not Applicable |
Background
6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP.