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Recombinant Human PGK1/PGKA Protein (His Tag)
SKU: PKSH032892-50
Recombinant Human PGK1/PGKA Protein (His Tag)
| SKU # | PKSH032892 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | Cell migration-inducing gene 10 protein, PGK1, PGKA, Phosphoglycerate kinase 1, Primer recognition protein 2 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ser2-Ile417 |
| Accession | P00558 |
| Calculated Molecular Weight | 45.5 kDa |
| Observed Molecular Weight | 37-50 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Phosphoglycerate kinase 1(PGK1) is an enzyme. It is mainly expressed in spermatogonia and Localized on the principle piece in the sperm. Its expression significantly decreased in the testis of elderly men. PGK1 involved in a critical energy-producing process known as glycolysis. It helps carry out a chemical reaction that converts a molecule called 1,3-diphosphoglycerate, which is produced during the breakdown of glucose, to another molecule called 3-phosphoglycerate during glycolysis. PGK1 may also act as a cofactor for polymerase alpha. The protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.