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Recombinant Human PHLDA2/BWR1C Protein (His Tag)
SKU: PKSH032887-50
Recombinant Human PHLDA2/BWR1C Protein (His Tag)
| SKU # | PKSH032887 |
| Expression Host | E.coli |
Description
| Synonyms | Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate Gene C Protein, Imprinted in Placenta and Liver Protein, Pleckstrin Homology-Like Domain Family A Member 2, Tumor-Suppressing STF cDNA 3 Protein, Tumor-Suppressing Subchromosomal Transferable Fragment |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Pro152 |
| Accession | Q53GA4 |
| Calculated Molecular Weight | 18.1 kDa |
| Observed Molecular Weight | 14-25 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM Nacl, 1mM DTT, pH 8.0. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Pleckstrin Homology-Like Domain Family A Member 2 (PHLDA2) is a peripheral membrane protein that belongs to the PHLDA2 family. PHLDA2 is expressed in the placenta and adult prostate gland. In the placenta, it is present in all cells of the villous cytotrophoblast. PHLDA2 plays a role in regulating placenta growth. PHLDA2 may act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.