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Recombinant Human PITPNA Protein (His Tag)
SKU: PKSH032889-50
Recombinant Human PITPNA Protein (His Tag)
| SKU # | PKSH032889 |
| Expression Host | E.coli |
Description
| Synonyms | PI-TP-Alpha, PITPN, PITPNA, Phosphatidylinositol Transfer Protein Alpha Isoform, PtdIns Transfer Protein Alpha, PtdInsTP Alpha |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Asp270 |
| Accession | Q00169 |
| Calculated Molecular Weight | 34.0 kDa |
| Observed Molecular Weight | 16&22&38 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM EDTA, 1mM DTT, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Phosphatidylinositol Transfer Protein α Isoform (PITPNA) is found in the cytoplasm and belongs to the PtdIns transfer protein family. PITPNA is a ubiquitous and highly conserved protein in multicellular eukaryotes that catalyzes the exchange of phospholipids between membranes and participates in cellular phospholipid metabolism, signal transduction and vesicular trafficking in vivo. It is expressed in a wide range of tissues and implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.